Goalkeeper and defence
?Hugo Lloris (Goalkeeper) – The French shot stopper is set to remain in goal despite a few nervous moments against Apoel and is the undisputed number one option.
Toby Alderweireld (Centre-back) – He is expected to line up as the right-sided defender of a back three and it gives him more license to push forward to showcase his passing qualities.
Davinson Sanchez (Centre-back) – He has managed to establish himself in the side following his summer arrival and is an ever-present this season.
Jan Vertonghen (Centre-back) – The first change is likely to see the Belgian return to the side after he missed the Champions League tie with suspension and has played every minute in the league so far.