Matteo Darmian, Phil Jones, Chris Smalling, Marcos Rojo
The defence is where we could witness several changes tonight with many of Manchester United’s squad players looking for first team opportunities.
Jose Mourinho has heaped praise on Antonio Valencia early in the season at right back but expect him, Eric Bailly and Luke Shaw to make away as Matteo Darmian, Phil Jones and Marcos Rojo achieve a start.
Elsewhere, Chris Smalling will be looking for minutes with Daley Blind representing somebody else who is unlikely to start following his mistake for Kevin De Bruyne’s opener in the Manchester Derby at the weekend.