Ronald Koeman has made four changes to his side to face Hajduk Split in the second leg of the Europa League play-off on Thursday night.
Everton travel to the Stadion Poljud in order to book their place in the group stages of the competition, with the odds firmly stacked against their Croatian opponents.
The Toffees have a 2-0 advantage from the first leg after Michael Keane and Idrissa Gueye gave the Toffees a first-leg advantage with two well-taken goals.
Koeman is without striker Sandro Ramirez who has a heel injury as well as Davy Klaassen who is sidelined with a foot injury after making only a substitute appearance against Manchester City on Monday night.
The Dutch manager hands a debut to club-record signing Gylfi Sigurdsson after he completed his £45million move to Goodison Park last week from Swansea.
Koeman has made four changes, bringing in Cuco Martina, Muhamed Besic, Ademola Lookman and Sigurdsson, who replace Mason Holgate, Phil Jagielka, Tom Davies and Gueye.
Everton posted the news on their official Twitter account prior to the match.
— Everton (@Everton) August 24, 2017
Jordan Pickford remains between the sticks for the Toffees, while Martina, Ashley Williams, Leighton Baines and Michael Keane form a back three for the Merseyside outfit.
Morgan Schneiderlin picked up a red card against Man City on Monday, but he starts alongside Besic in midfield, with Gueye dropping out.
New signing Sigurdsson starts on the left, while Lookman starts on the right as they look to support Wayne Rooney and Dom Calvert-Lewin who start up front.